DETECTING FUSION TRANSCRIPTS BY RNA SEQUENCING IN SCREENING TUMORS

What is a fusion gene? What are Chimeric RNAs? A fusion gene is a chimeric gene formed by the fusion of partial sequences of two genes, usually due to chromosomal translocations or deletions. These chimeric genes can form abnormal transcripts or proteins in subsequent biological processes, which can lead to or promote the development of tumors.

Introduction to Single-Cell RNA Sequencing RNA sequencing (RNA-seq) is a genomic technique for detecting and quantifying messenger RNA molecules in biological samples, which is useful for studying cellular responses. In recent years, RNA-seq has fueled a lot of medical discoveries and innovations. The approach is frequently applied to samples cont